Connecting Science and Society
Prolonged exposure to nitrate from contaminated water affects the transport of oxygen in blood. Nitrate can react with haemoglobin, oxidising it into methaemoglobin, which is unable to carry oxygen. High methaemoglobin levels among infants result in a medical condition known as methaemoglobinemia or blue baby syndrome. Dr Mina Sadeq and her team from the National Institute of Hygiene in Morocco, conducted two studies to investigate the combined effects of nitrate and bacteria on the development of methaemoglobinaemia in infants and young children.
Epilepsy is one of the most common causes of disability worldwide, but for many patients, treatment fails to be effective. Dr Victoria Morgan and her team from the Department of Radiology and Radiological Sciences at Vanderbilt University Medical Center are using functional connectivity mapping to find out why some patients respond better to treatment and what alternative ways there may be to tackle this debilitating disorder.
Dr Anton Iliuk – A Non-invasive, Low-cost Procedure to Detect Cancer Biomarkers from Biological Fluids
Liquid biopsies have recently gained attention as sources of non-invasive diagnostic cancer biomarkers. Traditional biofluid sampling methods, however, are onerous and time-consuming and present many limitations including poor sensitivity for biomarkers in low concentrations. Dr Anton Iliuk and his team at Tymora Analytical Operations, West Lafayette, USA, have developed a way to isolate extracellular vesicles from plasma, urine and other biofluids. They now aim to grow their network of collaborators to use their platform for the discovery of protein biomarkers from several cancers, neurodegenerative diseases, and other conditions.
Medical conditions that affect the brain can have severe impacts on people’s lives. Many of these conditions can be difficult to treat, including epilepsy which affects the brain to cause seizures and the common form of dementia known as Alzheimer’s disease. Dr Arun Swaminathan at the University of Nebraska Medical Center specialises in the treatment of epilepsy. He also collaborates with fellow researchers to explore treatment options for Alzheimer’s disease.
Applying mathematics to biology can help reveal the elusive details of life. Professor Wilfred D. Stein and his colleagues from the Hebrew University of Jerusalem and institutes worldwide have used quantitative tools to tackle topics ranging from cancer treatment to drug-resistant malaria, and lately, the evolution of the human genome. His extensive and broad work has supported scientists in many different areas of biomedicine and will leave a lasting impact on life science.
In recent years, scientific and technological advances have brought great innovation within the life sciences industry, introducing the need for entrepreneurship training for medical and engineering graduates. With this in mind, Michal Gilon-Yanai, Dr Robert Schneider and their collaborators developed an academic program designed to provide students and faculty members with the skills they need to become successful entrepreneurs. The team of collaborators includes Dr Gabrielle Gold-von Simson, an expert in implementing academic programs, and Dr Colleen Gillespie, who specialises in education, evaluation and dissemination science. Their pioneering program trains students on how to bring new biomedical technologies to the market.
TRANSFORMING GLOBAL HEALTH THROUGH SCIENTIFIC DISCOVERY As 2020 draws to a close and we look towards 2021, the importance of innovation and progress in science, medicine and healthcare has never felt more urgent or critical. Without doubt,...
BREAKING BOUNDARIES IN PHYSICS & TECHNOLOGY In this exciting edition of Scientia, we showcase some of the latest discoveries and innovations across the interconnected fields of engineering, technology and the physical sciences. To begin,...
BUILDING BRIGHTER FUTURES THROUGH INNOVATION IN PSYCHOLOGY AND NEUROSCIENCE This important and timely issue of Scientia showcases the scientists striving to build brighter futures for humankind through their pioneering endeavours across...
Modern industrial agriculture has helped farmers meet rising food demands, but these practices are contributing to a range of environmental problems. Regenerative agriculture holds promising solutions that could help to restore and maintain healthy ecosystems and contribute to climate change mitigation, while keeping pace with food demands and enhancing farmers’ resilience to environmental stressors. Through her research, Dr Hannah Gosnell aims to understand what motivates cattle and sheep farmers – also known as ranchers – to adopt and sustain the use of regenerative practices and what challenges must be navigated. Her work is informing efforts that encourage farmers to transition to these methods.
Since the turn of the century, a myriad of exciting applications for graphene have emerged. Amongst the most exciting might be its use as a scaffold for promoting tissue growth in the treatment of various medical conditions, including osteoarthritis. Researchers at Boise State University in the USA and Carl von Ossietzky University of Oldenburg in Germany are gaining a greater understanding of the interactions between graphene and cells, towards the development of implantable graphene-based devices that can rebuild damaged tissue.
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Vaccines were, arguably, the greatest medical advancement of the 20th century. Their safety and efficacy have improved significantly over the last few decades as new scientific evidence and technologies have developed. Long gone are the days of Edward Jenner scraping out cowpox blisters to deposit into scratches on uninfected people’s skin, as an early smallpox inoculation.
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