Hundreds of millions of years after the Big Bang, charged, ‘ionised’ particles not seen since the earliest ages of the universe began to re-emerge. Named ‘reionisation’, this event was crucially important in the history of our universe – but because it occurred so far back in the past, telescope observations can only offer astronomers limited clues about how it unfolded. In his research, Dr Nick Gnedin at the Fermi National Accelerator Laboratory uses advanced computer simulations to study reionisation. His team’s project, named ‘Cosmic Reionization On Computers’, or CROC, now offers a key resource to researchers studying this distant period.
The artificial synthesis of medicinal compounds that are typically derived from natural sources helps scientists to better understand how they function and deduce whether they can be enhanced. Unfortunately, the work involved in synthesising such natural compounds and their analogues is extremely difficult. Professor Hyun-Joon Ha and his team from Hankuk University of Foreign Studies in the Republic of Korea are exploring ways to transform compounds called aziridines into a range of biologically active molecules.
The far-reaching benefits of nanopore research encompass fields as diverse as physics, healthcare, big data processing and environmental studies. At the University of Illinois at Urbana-Champaign, Dr Jean-Pierre Leburton is conducting research focused on the use of nanopores in ultrathin solid-state molecular materials, such as graphene and 2D transition-metal dichalcogenides, for DNA sensing applications. This offers a low-cost and highly effective method of identifying biomolecules, and could have widespread medical applications, enabling rapid, early and effective disease diagnosis and prompting effective treatment, as well as providing invaluable technologies for assisting with DNA sequencing.
The rise of antibiotic-resistant strains of bacteria and the ubiquitous nature of mercury in the environment are two major health hazards and concerns faced today. Professor Maria Ngu-Schwemlein and her team from the Winston-Salem State University, USA, are addressing these issues by developing biomolecules that can bind and immobilise toxic mercury ions more effectively. Together with Professor Ngu-Schwemlein’s collaborators, the team is also investigating carbon nanodots as molecular scaffolds to enhance antibiotics in combating antimicrobial resistance.
Magnetic monopoles have long been dismissed as impossible by many physicists, but their existence has nonetheless been theorised for many decades. Through their extensive research, scientists at Terra Quantum AG, the University of Perugia, and SwissScientific Technologies, show that the end could soon be in sight for this conflict. The team’s investigations into superconducting materials not only show that magnetic monopoles must be real – their discoveries also set the stage for exciting technological advances.
The spaces in between galaxies may be unimaginably vast, but within galactic clusters, they are far from empty. Rather, these expanses are home to a wide range of interplaying, often violent plasma dynamics. In his research, Dr Tom Jones at the University of Minnesota plans to use cutting-edge computer techniques to simulate these processes – shedding new light on physical properties that have eluded astronomers so far. His team’s research will not only give crucial insights into some of the largest structures in the known universe, but will also capture the public imagination, and inspire a diverse new generation of astronomers.
Virtual and augmented reality technologies are now rapidly gaining traction in our society. Yet even as they improve, these devices continue to face major challenges relating to the wide variability of human vision. In their research, Dr Gordon Wetzstein and his colleagues at Stanford University explore innovative new ways to overcome these challenges, through the latest advances in both optics and vision science. In demonstrating ground-breaking innovations to near-eye displays and sensors, the team’s work could soon bring enormous benefits to users spanning a diverse spectrum of visual ability.
Enshrouding the Martian surface with thick clouds of dust, the Red Planet’s unique global dust storms have long mystified astronomers and planetary scientists. James Shirley, at NASA’s Jet Propulsion Laboratory, has shown through his research that the occurrence of these global storms is strongly linked to the changes in Mars’ motion about the gravitational centre of the solar system. Already boasting strong observational evidence, his results could not only improve our understanding of the Mars atmosphere – they may also lead to a better understanding of turbulent weather patterns on Earth.
Beginning 80 kilometres above Earth’s surface, and extending to the edge of the atmosphere, the thermosphere occupies a large proportion of Earth’s upper atmosphere. So far, studies of this expansive region have largely focused on how the air it contains flows over global scales. Now, Dr Ying Zou at the University of Alabama in Huntsville has explored how the thermosphere is also significantly influenced by ‘mesoscale’ interactions with Earth’s magnetosphere, creating flows spanning just hundreds of kilometres. Her team’s work could greatly improve our knowledge of how the upper atmosphere behaves.
Choosing which drug molecule to build is only one part of pharmaceutical research; medicinal chemists also need to know how to synthesise drug molecules in an efficient and cost-effective manner. Dr Oscar Verho and his team at Uppsala University in Sweden have made significant progress in this area and are aiming to reduce the time and resources needed to make drug compounds. The team is researching methods to ‘activate’ the carbon-hydrogen bonds that are commonly found in organic molecules to ultimately shorten the synthetic route to the required compound.
Climate change is mostly the result of elevated carbon dioxide emissions. Over the past two decades, research groups have been searching for new technologies that capture carbon dioxide from the atmosphere as an effective way of reversing climate change. Dr Radu Custelcean and his colleagues at the Oak Ridge National Laboratory in the US specialise in this endeavour. The team is developing novel materials and methods that filter carbon dioxide out of the air in an energy-efficient manner.
Radio frequency inteferometric lightning maps are important tools for researchers exploring the electrical processes that unfold within storm clouds. Dr Xuan-Min Shao and colleagues at Los Alamos National Laboratory in New Mexico, who first introduced broadband interferometry to lightning research over two decades ago, have now developed an advanced ‘beam steering’ interferometry technique to significantly improve the accuracy of lightning mapping. This approach, together with their recently developed polarisation detection technique, has begun to reveal new physics involved in lightning discharges. Their recent work shows how lightning initiation, which has been poorly understood until now, may be linked to high-energy cosmic particles entering Earth’s atmosphere.
Finding new and improved methods for purifying fuel gases, to both improve their efficiency and reduce their environmental impact, is an active area of research. Dr Matthew Lasich at Mangosuthu University of Technology in South Africa has been utilising computational modelling to discover how clay-based materials can increase the efficiency of fuel gas derived from wood and also reduce the amount of hydrogen sulphide found in natural and landfill gas.
The region of space in which Earth’s magnetic field interacts with flowing charged particles is home to a rich array of physical processes – but studying them is no easy task. Through a career spanning over 50 years, Dr Gerhard Haerendel at the Max Planck Institute for extraterrestrial physics has carried out world-leading research into these processes. His discoveries have now led to ground-breaking insights in the field of plasma physics – including explanations of striking arcs in the aurora, the discovery of characteristic prominences on the Sun’s surface, and analysis of artificial comets seeded directly into space.
Since the turn of the century, a myriad of exciting applications for graphene have emerged. Amongst the most exciting might be its use as a scaffold for promoting tissue growth in the treatment of various medical conditions, including osteoarthritis. Researchers at Boise State University in the USA and Carl von Ossietzky University of Oldenburg in Germany are gaining a greater understanding of the interactions between graphene and cells, towards the development of implantable graphene-based devices that can rebuild damaged tissue.
Dr Georgiy Stenchikov – Exploring the Effect of Aerosols on the Arabian Peninsula’s Changing Climate
Today, the Arabian Peninsula already faces a more daunting array of environmental challenges than most other regions on Earth. Yet as the climate changes, it is now expected to feel these adverse effects even more strongly in the coming decades. Using the latest modelling techniques, combined with ground-based observations, Dr Georgiy Stenchikov at King Abdullah University of Science and Technology in Saudi Arabia aims to make better predictions of how these changes will unfold. His work now provides critical guidance on how governments in the region should prepare for future shifts in climate and air quality.
Proteins are a fundamental building block of all living organisms. Knowing how to detect and quantify them and monitor their interactions is therefore vital in numerous different fields, from food science to pharmacology. Dr Anne Kleinnijenhuis and his colleagues at TRISKELION in The Netherlands specialise in the development of innovative analytical techniques for measuring proteins. Recently, they have been designing improved methods that have far-reaching applications in food preparation, pharmaceuticals and blood analysis.
Founded almost 50 years ago, the Association for Women in Science (AWIS) is a global network that inspires bold leadership, research, and solutions that advance women in STEM, spark innovation, promote organisational success, and drive systemic change. In this exclusive interview, we speak with AWIS president and world-renowned biomedical innovator Dr Susan Windham-Bannister, who describes the barriers that women face in the STEM workplace, and the many ways in which AWIS supports women in science and works towards eliminating inequality through systemic change.
Young people can often be discouraged from engaging with STEM subjects because they seem to have little obvious connection to their everyday lives. At Winston-Salem State University in North Carolina, an innovative program led by Dr Tennille D. Presley, is seeking to engage students by combining physics and biology with an art that is central to many students’ social lives: music. Early results from the program suggest that it has been successful in making science exciting and showing students that physics is involved in everything.
Machine learning is rapidly advancing the decision-making capabilities of today’s computers, yet without an in-depth knowledge of the programming it involves, many engineers and researchers find current technology inaccessible. Dr Paul Robertson at Dynamic Object Language Labs (DOLL) in Massachusetts believes that a solution to the issue may have been hidden in plain sight: machine learning itself. His ideas have now culminated in ‘Pamela’: a universal, open-source language capable of modelling real-world systems, and building plans to overcome challenges. The language and its related tools could soon open up significant opportunities in the emerging field of artificial intelligence.
Many kilometres above the Earth’s equatorial region, something strange occurs for several hours in the late evening: vast bubbles of plasma form in the upper atmosphere, which quickly rise upwards into space. Dr Joe Huba at Syntek Technologies in Virginia aims to gain a better understanding of this complex process, by recreating it through computer simulations. His team’s work is providing researchers with a more complete understanding of Earth’s atmosphere, and could also provide critical insights for satellite systems that communicate using radio waves, as well as global positioning systems.
Solution-processed nanomaterials, such as quantum dots, are some of the most exciting and widely studied materials in nanotechnology today, but reaching this point has been no easy task for scientists. From the very start of her career, Dr Ghada Koleilat, now an Assistant Professor at Dalhousie University in Canada, has been a renowned pioneer in this field – devising innovative new solutions to some of nanotechnology’s most pressing questions. Her numerous breakthroughs have brought about some profound new ways of thinking in one of the most rapidly developing energy generation technologies in the modern world: solar cells.
Sound waves are all around us. They govern vibrations from the sweetest of sound to the most destructive earthquakes. Now, a team of researchers across the US has embarked on an ambitious project, named ‘New Frontiers of Sound’, which will pave the way for advanced technologies that operate using sound waves. Combining the expertise of more than 30 leading scientists and engineers from across the field of acoustics, the project promises to discover new properties of sound, while offering exciting opportunities for researchers from a diverse range of backgrounds.
Located near the city of Pisa in Italy, the Virgo interferometer is the most sensitive gravitational wave detector in Europe. The latest version of the interferometer – the Advanced Virgo – was built in 2012, and has been operational since 2017. Virgo is part of a scientific collaboration of more than 100 institutes from 10 European countries. By detecting and analysing gravitational wave signals, which arise from collisions of black holes or neutron stars millions of lightyears away, Virgo’s goal is to advance our understanding of fundamental physics, astronomy and cosmology. In this exclusive interview, we speak with the spokesperson of the Virgo Collaboration, Dr Jo van den Brand, who discusses Virgo’s achievements, plans for the future, and the fascinating field of gravitational wave astronomy.
Cancer is one of the most common causes of mortality worldwide and diagnosis rates are continually increasing. An estimated one in three women and one in two men will be diagnosed with a form of cancer at some point throughout our lives. For many cancer types, chemotherapy and radiotherapy are the chosen treatment methods, but their success rates are surprisingly limited, and both can cause serious side-effects. Dr Afsaneh Lavasanifar and her research group at the University of Alberta have set out to develop drug-delivery systems to improve the effectiveness of cancer treatment and reduce side-effects. Their research involves the targeted delivery of drug-loaded nanoparticles directly to tumour tissues.
It is undoubtable that virtual reality and augmented reality will soon be an integral part of our daily lives at home, in education, and at work. Here, we look at some of the exciting projects that Dr William Hurst of the Department of Computer Science at Liverpool John Moores University is driving forward and read how he is embracing virtual reality and augmented reality to enhance teaching and education, providing insight into how such technology may be utilised in the not too distant future.
By precisely measuring path differences in light waves as they are split apart and recombined, interferometers have allowed physicists to make some of their most profound discoveries: from disproving the ether theory in the late 19th century, to the first detections of gravitational waves in 2016. Now, Dr Stephanie Manz and Dr Thorsten Schumm at TU Vienna aim to push the capabilities of interferometers further with iWave: an instrument that exploits particle-wave-duality, one of the fundamental principles of quantum mechanics. By replacing light waves with matter waves, the duo and their team believe that their new interferometer could bring about exciting experimental opportunities.
Using laser light to produce and receive high-frequency radiation, photoconductors have become a promising aspect of materials science in recent years. So far, however, their production has faced a number of barriers. Through his research, Dr Sascha Preu at TU Darmstadt in Germany has tackled many of these challenges through the use of an alloy based on indium gallium arsenide enhanced with erbium arsenide particulates, whose electrons display some intriguing properties. His team’s work has now greatly improved the prospects for photoconductors in applications including spectroscopy, imaging and non-destructive testing.
Dr Mike Müller-Petke | Dr Stephan Costabel – Enhancing Groundwater Detection with Magnetic Resonance
Detecting underground water is of considerable importance, particularly for applications such as groundwater exploration, predicting the movement of contaminants in soils or building underground tunnels and mining facilities. Underground water is a limited resource that is essential for human life, but it can pose a safety threat in cases where the structural integrity of underground structures, such as tunnels, depends on solid earth being present throughout. Dr Mike Müller-Petke of the Leibniz Institute for Applied Geophysics, and Dr Stephan Costabel of the Federal Institute for Geosciences and Natural Resources, are investigating methods to greatly improve the detection of underground water, using a technology known as nuclear magnetic resonance.
From brown dwarfs to supermassive black holes, many of the strangest objects known to astronomers are formed as material collapses in on itself under its own gravity. Through a combination of physical theories and the latest computer simulations, Dr Shantanu Basu at the University of Western Ontario in Canada is offering intriguing new insights into how these structures originate. His theories could help astronomers to understand the very earliest stages of bodies ranging from those too small to become stars, to the vast, all-devouring heavyweights that reside in the centres of galaxies.
When the Sun’s surrounding corona erupts, colossal streams of charged particles are ejected out into interplanetary space, and go on to interact with the material that resides there. Dr Robert Ebert at the Southwest Research Institute and his colleagues combine observations from spacecraft with the latest computer models to uncover the mysteries of these interactions. Their research focuses on advancing astronomers’ understanding of the highly energetic processes that play out in the void that comprises over 99% of the Solar System’s volume.