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Dr Khaled Mnaymeh | Does a Boundary Exist Between Classical and Quantum Mechanics?

Physicists typically have two frameworks for considering mechanics – a classical picture, looking at larger-scale objects, or a quantum picture, considering things on a subatomic scale. Where the boundary between these two pictures lies is an open question. Dr Khaled Mnaymeh from National Research Council Canada and Carleton University argues that this boundary does not exist. Through his analysis of Bell’s inequality, configuration space, and counterfactual definiteness, his work highlights the importance of considering these foundational principles in our study of the world around us.

Dr Kenric Nelson | Modelling the Extreme: A New Technique for Training Risk-Aware Artificial Intelligence

Category 5 hurricanes, financial crashes, and global pandemics are just a few examples of rare events whose high risks necessitate understanding and mitigation. Developments in artificial intelligence (AI) could go a long way towards improving our ability to model and mitigate the impacts of such extreme events, but current training methods are often unable to deal effectively with outliers in data – which is exactly what extreme events are. If outliers are present in training data, they skew the AI’s expectations, but if they’re omitted entirely, models will wrongly assume they never occur. To address this shortcoming, the Photrek team, led by Dr Kenric Nelson, has developed a new training technique to design more robust AI systems that can cope with rare, extreme events.

Professor Yi-Gang Xu | It’s Written in the Stones – New Moon Rock Samples Demand a Rethink of Lunar Cataclysm Theory

A significant debate continues between scholars in the astronomical community regarding the early history of our solar system. It’s been hypothesised that the solar system experienced a dramatic cataclysm a short while —in cosmological terms— after the Earth and Moon solidified. Dubbed the Late Heavy Bombardment theory, disturbances in gas giant orbits may have caused a sudden hailstorm of comets and asteroids to be hurled towards the inner planets. Lunar rock samples collected from craters during Apollo missions seemed to support the idea, but new evidence is demanding a rethink.

Professor Yi-Gang Xu and his team examined samples recovered from the Chang’e-6 mission in 2024, and they suggest a more gradual change in the frequency of asteroid impacts, rather than a sudden, violent cataclysm.

Professor Dilip Kumar | From the Ground Up: The Making of a Modern Mathematics Centre in Kerala

In 1977, Professor Aleyamma George, head of statistics at Kerala University, dreamed of establishing a new centre for mathematical sciences in Kerala’s coastal capital Trivandrum. Her mission was to encourage talented young mathematicians to engage in frontline research in the mathematical sciences. But, for many years, it struggled to obtain regular government funding and survived only because of the Herculean efforts and personal funds of both Prof George and its Director since 1985, Professor Arak Mathai.
Later, it supported the operations of eight different dedicated research groups producing award-winning work, and regularly hosts undergraduate-level workshops; it fulfilled the original mission of training and educating new generations of mathematicians, so that they may contribute to cutting-edge, internationally recognised research.

Dr Ray Stewart | Barriers to Dental Care for People with Special Needs: A Crisis of Neglect and Inaction

For people with special healthcare needs, something as basic as visiting a dentist can be nearly impossible. A ground-breaking paper by researchers at the University of California, San Francisco (UCSF) exposes the scale of this crisis. By outlining potential paths forward, Dr Ray Stewart and Dr Ben Meisel offer hope for significant improvements in access to essential dental care.

Dr Liisa Laakso | Lighting the Way: Exploring Photobiomodulation to Ease MELAS

MELAS is a rare and serious genetic condition that affects how the body’s cells produce energy, leading to extreme fatigue, muscle weakness, and a range of other symptoms. With no cure currently available, treatment focuses only on managing complications.
A team of researchers led by Dr Liisa Laakso at the Mater Research Institute-University of Queensland, Australia, is exploring an innovative, non-drug therapy called photobiomodulation, which uses light to stimulate mitochondria to work more efficiently. This pioneering study will provide intial evidence on whether PBM can safely reduce fatigue and improve quality of life for people living with MELAS, paving the way for future clinical trials.

Professor John Paul Pezacki, PhD, FRSC (UK) | Engineering Proteins for the Prevention of Disease Progression

The way in which viruses invade and replicate within their hosts involves a multilayered system of protein-based interactions, and understanding the mechanisms at play is crucial when developing potential treatments. Utilising new techniques such as genetic code expansion, Professor John Paul Pezacki and his team of researchers at the University of Ottawa in Canada have designed a novel, highly specific artificial protein complex which can halt the progression of viral infections in human cells. They have identified and described a novel approach to wider preventative and restorative therapeutics in human disease.

Professor Jun Tsuji – Professor Steven Wathen | SHAPE STEM: Building a Sustainable Future through STEM Education

The SHAPE STEM program at Siena Heights University is transforming how students engage with science, tackling urgent environmental challenges in Michigan while preparing the next generation of problem-solvers. Led by Professor Jun Tsuji and Professor Steven Wathen, the program combines research, mentorship, and financial support to help low-income and underrepresented students thrive in STEM, with outcomes that ripple far beyond the classroom.

Assistant Professor Matjaž Gomilšek | Ghost in the Material: Using Muons to Study the Effects of Quantum Jitters

Nothing can ever be perfectly still, no matter how cold you make it. Take solid nitrogen, for example, which freezes at a bone-chilling -210 °C. You might expect its molecules to be frozen rigidly in place but, even at such extreme temperatures, they have a life of their own. At the microscopic level, quantum effects become important and random fluctuations ensure that molecules of solid nitrogen will jitter unceasingly. In the limit of absolute zero temperature, these tiny movements can have a considerable influence on the properties and behaviour of whole materials. New work published by a collaboration of scientists from Slovenia and the UK has sought to develop a better understanding of the effects of this quantum motion.

Nick Martin | The Future of Floods: Smarter Risk Tools for Sustainable Water Management in a Changing Climate

Sustainable decision-making requires balancing the costs borne by today’s society with those that will fall on future generations. Climate change is intensifying extreme weather, making floods more severe because a warmer atmosphere can hold and deliver a larger volume of water as precipitation. It may also be the case that severe floods are becoming more frequent as drought becomes more frequent, average conditions rarely occur, and weather oscillates between short duration wet and long duration dry extremes. Worryingly, traditional infrastructure (often designed using outdated, backward-looking models) risks failing under these evolving conditions.
Nick Martin from Vodanube LLC, and his colleagues have applied Probabilistic Risk Assessment (PRA) to flood inundation. Their research optimises current adaptation and future mitigation strategies, even while acknowledging PRA’s limitations. The team demonstrates how this approach can guide more resilient water resource management, and highlights opportunities for further study.

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Earth & Environmental Sciences

Nick Martin | The Future of Floods: Smarter Risk Tools for Sustainable Water Management in a Changing Climate

Nick Martin | The Future of Floods: Smarter Risk Tools for Sustainable Water Management in a Changing Climate

Sustainable decision-making requires balancing the costs borne by today’s society with those that will fall on future generations. Climate change is intensifying extreme weather, making floods more severe because a warmer atmosphere can hold and deliver a larger volume of water as precipitation. It may also be the case that severe floods are becoming more frequent as drought becomes more frequent, average conditions rarely occur, and weather oscillates between short duration wet and long duration dry extremes. Worryingly, traditional infrastructure (often designed using outdated, backward-looking models) risks failing under these evolving conditions.
Nick Martin from Vodanube LLC, and his colleagues have applied Probabilistic Risk Assessment (PRA) to flood inundation. Their research optimises current adaptation and future mitigation strategies, even while acknowledging PRA’s limitations. The team demonstrates how this approach can guide more resilient water resource management, and highlights opportunities for further study.

Physical Sciences & Mathematics Latest

Dr Khaled Mnaymeh | Does a Boundary Exist Between Classical and Quantum Mechanics?

Dr Khaled Mnaymeh | Does a Boundary Exist Between Classical and Quantum Mechanics?

Physicists typically have two frameworks for considering mechanics – a classical picture, looking at larger-scale objects, or a quantum picture, considering things on a subatomic scale. Where the boundary between these two pictures lies is an open question. Dr Khaled Mnaymeh from National Research Council Canada and Carleton University argues that this boundary does not exist. Through his analysis of Bell’s inequality, configuration space, and counterfactual definiteness, his work highlights the importance of considering these foundational principles in our study of the world around us.

Engineering & Computer Science Latest

Dr Kenric Nelson | Modelling the Extreme: A New Technique for Training Risk-Aware Artificial Intelligence

Dr Kenric Nelson | Modelling the Extreme: A New Technique for Training Risk-Aware Artificial Intelligence

Category 5 hurricanes, financial crashes, and global pandemics are just a few examples of rare events whose high risks necessitate understanding and mitigation. Developments in artificial intelligence (AI) could go a long way towards improving our ability to model and mitigate the impacts of such extreme events, but current training methods are often unable to deal effectively with outliers in data – which is exactly what extreme events are. If outliers are present in training data, they skew the AI’s expectations, but if they’re omitted entirely, models will wrongly assume they never occur. To address this shortcoming, the Photrek team, led by Dr Kenric Nelson, has developed a new training technique to design more robust AI systems that can cope with rare, extreme events.

Arts, Humanities & Social Sciences Latest

Police Body Worn Cameras in Rio’s Favelas: Can Technology Reduce Violence?

Police Body Worn Cameras in Rio’s Favelas: Can Technology Reduce Violence?

In 2016, a team of three researchers based at Stanford University —Beatriz Magaloni, Vanessa Melo, and Gustavo Robles— conducted a groundbreaking experiment in Rocinha, Rio de Janeiro’s largest favela (informal settlement), to test whether body-worn cameras (BWC) could reduce police violence and improve community relations.
The findings reveal that body cameras hold great promise, but they also come with serious challenges. Before the experiment started, one police unit commander ominously told the researchers: “If you give body cameras to my officers, this will stop them from doing their job.”

Life Sciences & Biology Latest

Dr George B Stefano | Mitochondria Reconsidered: Unmasking the Ancient Bacterial Legacy in Human Health

Dr George B Stefano | Mitochondria Reconsidered: Unmasking the Ancient Bacterial Legacy in Human Health

Although often described simply as the cell’s powerhouse, mitochondria began life as bacteria and still carry many bacterial traits. Dr George Stefano, Visiting Professor at Charles University, Prague, explores whether mitochondria should be seen not only as symbiotic partners but also as the most successful chronic infection in history. He highlights how this perspective sheds light on human resilience, viral tolerance, and long-term health. By reframing mitochondria in this way, Dr Stefano and colleagues invite a broader conversation about ageing, disease, and the fine balance between host and microbe that continues to shape human biology today.

Shirley C. Strum | Learning from baboons

Shirley C. Strum | Learning from baboons

 Article written by Sophie Langdon, PhDShirley C. Strum has spent over 50 years studying wild baboons in Kenya. During that time, she has pioneered new ideas about baboons, about society, about nature, about science and about evolution. As she recounts in her new...

Education & Training Latest

Professor Dilip Kumar | From the Ground Up: The Making of a Modern Mathematics Centre in Kerala

Professor Dilip Kumar | From the Ground Up: The Making of a Modern Mathematics Centre in Kerala

In 1977, Professor Aleyamma George, head of statistics at Kerala University, dreamed of establishing a new centre for mathematical sciences in Kerala’s coastal capital Trivandrum. Her mission was to encourage talented young mathematicians to engage in frontline research in the mathematical sciences. But, for many years, it struggled to obtain regular government funding and survived only because of the Herculean efforts and personal funds of both Prof George and its Director since 1985, Professor Arak Mathai.
Later, it supported the operations of eight different dedicated research groups producing award-winning work, and regularly hosts undergraduate-level workshops; it fulfilled the original mission of training and educating new generations of mathematicians, so that they may contribute to cutting-edge, internationally recognised research.

Psychology & Neuroscience Latest

Professor Hong-Wei Dong | Mapping the Mind’s Command Centre for the Body

Professor Hong-Wei Dong | Mapping the Mind’s Command Centre for the Body

The brain’s ability to manage stress and guide behaviour, including making decisions or interacting with others, relies in part on an area called the medial prefrontal cortex. But exactly how this region controls the body’s internal responses has remained unclear. New research on mice led by Prof Hong-Wei Dong and his team at the University of California Los Angeles (UCLA) sheds light on a little-studied part of the brain that may play a key role.
The work reveals a complex network, unconvering a previously undefined “primary visceromotor cortex” in the mouse brain, that helps link thoughts, feelings, and physical state. This discovery could reshape our understanding of how the brain controls stress, emotion, and internal bodily functions, and offer new insights into human mental health disorders.

Business, Economics & Finance Latest

Professor David Gerbing | A Quick and Easy New Way to Visualise Data

Professor David Gerbing | A Quick and Easy New Way to Visualise Data

Do you find data analysis dense and impenetrable, like a quantitative jungle? You’re not alone. Many of the most useful statistical tools have steep-learning curves and often demand both sophisticated mathematical ability and advanced programming skills. But, in a world where data is constantly generated and recorded, it’s essential that data analysis tools are as accessible as possible. And there’s no reason they can’t be; with such powerful digital tools at our disposal, data visualisation can be made as straightforward as the click of a button.

That’s the goal behind Professor David Gerbing’s latest project – lessR. lessR is a free, open-source package for one of the most popular analysis programming languages, R, designed to make data visualisation as simple as possible. See Professor Gerbing’s written and video introduction to using the R language for data analysis at the website he provides for his students.

Latest Issues
Scientia Issue #155 | Our future relies on teaching of the past

Scientia Issue #155 | Our future relies on teaching of the past

This is the second issue of Scientia in its newest life. Our new Editor-in-Chief is Maria Machado, a physiologist turned consultant. You may not have noticed, but you met Maria when reading about gender in our previous issue. Previously, Maria has worked with Bio-Protocol, Editage, and Enago to suggest revisions before ‘Reviewer 2’ demands them. Because of this background, and due to her role as co-Chair of Peer Review Week, she has made some changes to how we present ourselves and work with researchers — we will present the research as a value to society at large, and talk about researchers’ motivations.

Scientia Issue #150 | Big Ideas for a Better World

Scientia Issue #150 | Big Ideas for a Better World

Big Ideas for a Better World This riveting issue of Scientia showcases some of the biggest new ideas across science, research, and technology. While we face many challenges, from climate change to cancer, epidemics to economic...

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